Dried Gold Nanoparticles
NanoComposix’s dried gold nanopowders are formulated with polymer or alkanethiol surface coatings which allow the nanoparticles to easily be redispersed as unagglomerated dispersions in a variety of solvents. We have verified the redispersion with transmission electron microscopy (TEM), UV-visible spectroscopy and dynamic light scattering. Please contact us if you would like other sizes.
N NanoXact, 0.05 mg/mL. Narrow size distribution, wide variety of surfaces.
D NanoXact, dried. Available only with PVP.
B BioPure, 1 mg/mL. Purified and concentrated NanoXact. Sterile and endotoxin-free. (Not available dried.)
E Econix, 5 mg/mL. Larger quantities, lower cost.
D Econix, dried. Available only with PVP.
Organic (non-polar: hexane, toluene, chloroform, etc.)
Dodecanethiol-Stabilized Gold Nanopowders
- Unagglomerated after dispersion into hexane, toluene, chloroform and many other organic solvents
- Dodecanethiol capping agent
- Available with a size of 2 nm, 4 nm, and 5 nm with CV’s <20%.
PVP-Stabilized Gold Nanopowders
- Unagglomerated after dispersion into water, DMF, acetonitrile, methanol and many other solvents
- Polyvinylpyrrolidone (PVP) surface coating (0.1–0.5% PVP as excipient)
- Sizes ranging from 5–100 nm with narrow distributions, CV’s <15% (<25% for Econix)
Gold Nanoparticle Applications
Gold nanopaticles are readily conjugated to antibodies and other proteins due to the affinity of sulfhydyl (-SH) groups for the gold surface, and gold-biomolecule conjugates have been widely incorporated into diagnostic applications, where their bright red color is used in home and point-of-care tests such as lateral flow assays.
Gold nanomaterials can be conjugated to biomolecules to specifically target cancer cells, and used for photothermal cancer therapy, where their tunable optical properties cause them to convert laser light into heat and selectively kill cancerous cells.
Gold nanoparticles have unique optical properties because they support surface plasmons. At specific wavelengths of light the surface plasmons are driven into resonance and strongly absorb or scatter incident light. This effect is so strong that it allows for individual nanoparticles as small as 30 nm in diameter to be imaged using a conventional dark field microscope. This strong coupling of metal nanostructures with light is the basis for the new field of plasmonics. Applications of plasmonic gold nanoparticles include biomedical labels, sensors, and detectors. The gold plasmon resonance is also the basis for enhanced spectroscopy techniques such as Surface Enhanced Raman Spectroscopy (SERS) and Surface Enhanced Fluoressence Spectroscopy which can be used to detect analytes with ultrahigh sensitivity.